Migraine, a debilitating neurovascular disorder, is often associated with vascular complications such as ischemic stroke. Strategies to improve endothelial function can play a crucial role in managing and preventing these complications. Yoga, known for its positive impact on the cardiovascular system, has been considered as a potential intervention. However, until now, no randomized controlled studies have explored the effects of yoga on the endothelial function of individuals with migraine.
In 2014, a study conducted by Hajar Naji-Esfahani and colleagues, 42 female migraine patients were recruited and randomly assigned to one of two groups: a Yoga exercise group or a control group. The control group received standard medical treatment for 12 weeks, while the Yoga group underwent a structured yoga training program in addition to the same medical regimen. Blood samples were collected from all participants to measure the plasma levels of intercellular adhesion molecule (ICAM) and vascular cell adhesion molecule (VCAM) after the completion of the yoga intervention.
Out of the initial 42 participants, 32 completed the study (Yoga group: n = 18, Control group: n = 14). A comparative analysis of the data collected from the two groups following the 12-week intervention revealed noteworthy findings. Notably, there was a significant reduction in the plasma levels of VCAM in the Yoga group as compared to the Control group (15.29 ± 2.1 ng/ml vs. 21.70 ± 3.0 ng/ml, P < 0.05). In contrast, no significant difference was observed in ICAM levels between the two groups (19.1 ± 1.8 ng/ml vs. 20.97 ± 1.9 ng/ml, P > 0.05).
The study’s results suggest that incorporating yoga exercises as a complementary treatment alongside pharmacological interventions may offer a promising approach to enhance vascular function in individuals suffering from migraines. The significant decrease in VCAM levels indicates the potential for yoga to positively influence endothelial function, which is critical for preventing vascular complications associated with migraine. This research sheds light on the potential benefits of a holistic approach to migraine management, and further investigation is warranted to better understand the underlying mechanisms and long-term effects of yoga as an adjunct therapy for migraineurs.
Reference: Naji-Esfahani, H., Zamani, M., Marandi, S. M., Shaygannejad, V., & Javanmard, S. H. (2014). Preventive effects of a three-month yoga intervention on endothelial function in patients with migraine. International Journal of Preventive Medicine, 5(4), 424.