In 2004, A randomized controlled trial conducted by Alessandro Crippa, et. al., investigated the efficacy of Grimaldi’s method in improving muscle function among individuals with multiple sclerosis (MS). This therapeutical approach targeted the hip abductors, aiming to enhance active muscle recruitment.

In the study, forty MS patients were randomly assigned to either the Grimaldi’s group or the control group, with 20 participants in each. Over the course of three treatment sessions, the researchers assessed various parameters including active range of motion against gravity (AROM), maximum isometric endurance (END), and maximum mechanical work (WORK) of the hip.

The results revealed a significant improvement in AROM among participants in the Grimaldi’s group, with an increase from 21.4 degrees to 37.2 degrees. However, there were no notable improvements in END parameter. Remarkably, there was a substantial enhancement in mechanical work, rising from 103.9 Nm to 149.6 Nm following the Grimaldi’s treatment.

These findings suggest that Grimaldi’s method holds promise in augmenting muscular recruitment of the hip abductors, thereby improving active range of motion and mechanical work in MS patients. This novel therapeutic approach offers potential benefits for individuals with MS, potentially contributing to enhanced mobility and overall quality of life. Further research is warranted to explore the long-term effects and broader applicability of Grimaldi’s method in MS rehabilitation.

Reference: Crippa, A., Cardini, R., Pellegatta, D., Manzoni, S., Cattaneo, D., & Marazzini, F. (2004). Effects of sudden, passive muscle shortening according to Grimaldi’s method on patients suffering from multiple sclerosis: a randomized controlled trial. Neurorehabilitation and neural repair, 18(1), 47-52.