What is the cost-effectiveness of spinal manipulation for low back pain? Insights from the UK BEAM trial

In a pioneering endeavor to evaluate the cost-effectiveness of incorporating spinal manipulation and exercise interventions into primary care for individuals seeking relief from low back pain, the UK BEAM Trial Team (2004) conducted a rigorous analysis. Their objective was to determine the economic viability of adding spinal manipulation, exercise classes, or a combination of both to the standard “best care” protocol in general practice settings across the United Kingdom.

The trial, characterized by its pragmatic design with a factorial setup, unfolded across 181 general practices and 63 community settings, spanning 14 centers throughout the UK. The participants, totaling 1287 individuals, accounted for a remarkable 96% of the initially enrolled 1334 subjects.

Key outcome measures included healthcare costs, quality-adjusted life years (QALYs), and the cost per QALY assessed over a 12-month period. Results revealed distinct cost profiles for each intervention: manipulation incurred a mean treatment cost of £195, exercise £140, and combined treatment £125 relative to “best care.” Notably, all active treatments demonstrated an enhancement in participants’ average QALYs compared to standard care alone.

Upon closer scrutiny, the analysis delineated the incremental cost-effectiveness ratios (ICERs) for the interventions. Combined treatment exhibited an ICER of £3800 per additional QALY relative to best care, positioning it as a promising economic choice. In contrast, manipulation alone boasted an ICER of £8700 compared to combined treatment, underscoring its favorable cost-effectiveness.

Moreover, the study delved into hypothetical scenarios reflecting the National Health Service’s (NHS) willingness to pay for additional QALYs. With a threshold of £10,000 per extra QALY, manipulation alone emerged as a potentially optimal strategy, provided manipulation followed by exercise was not an option. In such a scenario, exercise would present an ICER of £8300 relative to best care.

In sum, the findings from the UK BEAM Trial underscore the cost-effectiveness of spinal manipulation as an adjunct to standard care for low back pain in primary care settings. While manipulation alone may offer superior value for money compared to combined treatment, the nuances of healthcare economics warrant careful consideration in treatment decision-making.

Reference: Uk, B. E. A. M. (2004). United Kingdom back pain exercise and manipulation (UK BEAM) randomised trial: cost effectiveness of physical treatments for back pain in primary care. Br Med J329, 1381-1385.

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