Post-test Probability

Post-test probability: is the probability of the presence of a disease after a confirmatory diagnostic test. Method I:  Let us estimate post-test probability by hand calculation using the data from the study by Capra et al (1). To do this, we need to know the pre-test probability and the positive likelihood ratio values. For this purpose, let us assume the pre-test probability as 0.55. And, we will … Continue reading Post-test Probability

Likelihood Ratios

Let us continue using the data from the study by Capra et al (1). The likelihood ratio is the percentage of diseased individuals with a given test result divided by the percentage of healthy individuals with the same test result (2). The likelihood ratios (positive and negative) can be calculated by using the following formulae (2): + LR = sensitivity / (1- specificity) = True positive rate / … Continue reading Likelihood Ratios