True Rates

In this section, the true positive and negatives rates of diagnosing a disease using a clinical test (eg., SLR) compared against a gold standard test (in this instance, MRI) will be calculated. Let us use the following data from a peer-reviewed article for our analysis (1). In this study, the patients who had lumbar MRI grades 2 to 5 (gold standard criteria) were considered having the disease. Now, let … Continue reading True Rates

Pre-test Probability

Pre-test Probability: It is defined as the probability of a patient having the suspected disease before application of a diagnostic test. Determining the pre-test probability is the first step in making a clinical diagnosis.   Pre-test Odds: It is defined as the odds that a patient has the suspected disease before application of a diagnostic test. References: Šimundić, A.M., 2009. Measures of diagnostic accuracy: basic definitions. EJIFCC, … Continue reading Pre-test Probability